‘Vitamin B3 can miscarriage prevention’

‘Vitamin B3 can miscarriage prevention’

Photo: Hollandse Hoogte

Niacin, better known as vitamin B3, it would be very effective in the prevention of miscarriages or birth defects. That report scientists after research into the influence of niacin.

The researchers looked at the genes of four families in which a lot of miscarriages and birth defects occurred. There were two gene mutations to the front, that had an impact on the production of nicotinamideadeninedinucleotidefosfaat (NAD), a molecule that is crucial for the development and recovery of genes.

They are not as easy these mutations after in muizenembryo’s and discovered in the born babymuizen the same birth defects as encountered in the human babies. Both had a shortage of NAD.

As vitamin B3 in the form of niacin is transformed into NAD, and decided the scientists the supplement to add to the drinking water of pregnant mice. Then found out that the birth defects had vanished. All born mice appeared to be in excellent health.


The researchers say that the next step of this research is to test to develop that the NAD content of pregnant women can be measured. Women in whom this layer is apparent, extra vitamin B3 taking. This will probably be in a different form than the existing vitamin B3 pills: that may not be sufficient for such a shortfall.

“This has the potential to be a number of miscarriages and birth defects drastically reduce,” says Sally Dunwoodie from the Victor Chang institute.

Niacin – or vitamin B3 is also present in meat, fish, wholegrain cereals, vegetables and potatoes.

The research was published Thursday in The New England journal of medicine.

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