Protein discovered that aggressive cancer can predict
Researchers at the Antoni van Leeuwenhoek have a protein discovered that the progression of the aggressive cancer neuroblastoma can predict.
According to the hospital’s going to be an important discovery, because there is yet but little is known about this form of cancer.
Neuroblastoma is one of the most common forms of cancer in very young children. Yet the disease is relatively rare.
In the Netherlands, about 35 children per year affected by it. Striking feature of neuroblastoma is that the tumor sometimes by itself disappears, especially in the youngest children (children under two). But in older children the tumor grows often especially if the gangrenous, he is very difficult to treat.
In the hope of new treatments worldwide, research into the origin of these tumors. The research group of Antoni van Leeuwenhoek discovered that a particular protein ‘GDE2’ plays an important role in this biological puzzle.
Patients with many of these proteins in their tumor prove to be much more favourable prospects than children with few of these substances. The corresponding proteins, among other things, that the cancer cells are less easily by the body can spread.
According to the Antoni van Leeuwenhoek is the discovery an important step in the future development of new drugs.
The research was conducted in cooperation with the AMC. The results were published Thursday in the prestigious journal Cancer Cell.