Ear infection is partly genetically determined
Researchers from the Erasmus MC have a gene found that children more or less susceptible to an ear infection. Inflammation of the ear would, therefore, partly hereditary to be determined.
It is the first time that researchers have discovered that the get of ear infections in children co-hereditary is determined.
Children with a certain variation in their DNA are more susceptible to ear infections than peers without this genetic predisposition, as is read in the research has been published in the scientific journal Nature Communications, that has recently appeared.
The researchers compared the DNA of 13,000 children with ear infections and children who had to. They found that children with a certain variant of the FNDC1 gene, responsible for a substance that plays a role in the clean-up of inflammation, is more sensitive for ear infections than other children.
In addition, in mice demonstrated that the FNDC1 gene actually is in the ear, and in mice with ear infections more expressed, than in mice without an active ear infection.
The most common
An ear infection with loopoor result is one of the most common infectious diseases in childhood, and causes a lot of doctor visits. Gijs van Ingen, ENT doctor in training: “We have for the first time a gene is discovered, which helps us to understand why one child suffers more of looporen, while at the other there is actually very little to do.”
Previously it was focused on environmental factors that increase the chances of looporen can increase. Think of the number of brothers and sisters, or to visit a nursery. “Our study shows that genetic predisposition indeed plays a part. An ear infection is for a child is a very painful and nasty disease. We hope that this study contributes, that in the future a child that is prone to ear infections faster than it can be recognized, and may be different or faster to be treated.”
Follow-up research should reveal the extent to which environmental factors and DNA affect each other.