Bacteria in stool patient with Crohn’s disease appear to be predictors
The composition of bacteria in the stool of patients with crohn’s disease appears to be a predictor of disease activity. The measuring of the bacteria in the stool offers a possible alternative to an endoscopy.
The Maastricht UMC writes that an endoscopy, in which the intestines with a camera watching, expensive, invasive, and not all are free of potential complications.
For the study the researchers compared the stools of 71 patients with Crohn’s disease, from which almost two hundred monsters pulled: 97 active and 97 in a quiet period.
A specific bacteria profile appeared to distinguish between patients in the active phase and patients in the remission phase. In one period, certain bacteria are more present and less in the other (and vice versa). In almost 80 percent of the cases, predicted a certain composition of bacteria is correct whether a patient is in the active phase of the disease was.
Crohn’s disease is a chronic inflammatory disease of the intestine. The disorder is often interspersed with relatively quiet periods (called a remission) and active periods with sudden worsening of symptoms (abdominal pain, fatigue, blood loss). Patients therefore need regular check-ups with the specialist for timely intervention.
“Although further research is required, this method in the future may be an efficient and patient-friendly alternative for the regular performing of an endoscopy,” said lead researcher dr. Daisy Jonkers of the Maastricht UMC+. In addition, like the Maastricht scientists focus on research into changes in the composition of bacteria in the course of time. So would a worsening of the disease as possible, even earlier can be found.